DARe Research Scientist, Age-related Diseases

Internal Job Title – Research Scientist I/II

Position Location: Cambridge, MA, onsite

The Diseases of Aging and Regenerative Medicine (DARe) in Cambridge is seeking for a highly motivated BS/MS level scientist to join our early stage exploratory and drug discovery department. Our group is developing new therapies for age-related diseases, exploring disease biology understanding and potential treatments including target identification, validation and subsequent developing therapeutic interventions. In the role, you will be working on exploratory and drug discovery projects in age-related diseases. Your role involves developing complex in vitro assay and aging systems, in particular iPSC-derived cardiac, muscular and neuromuscular 2D and 3D models and phenotypical assay systems with a broad range of readout and, in addition, ex vivo exploration of novel biomarkers and readouts in disease models using emerging technologies. You will be part of an interdisciplinary, highly collaborative group. 

-    Perform molecular and cellular biology techniques to support exploratory and drug discovery projects in DARe.

-    Apply a diversity of in vitro techniques to identify and validate assays and characterize cellular models of disease.

-    Apply a diversity of ex vivo techniques to assess preclinical and human samples for pharmacodynamic biomarkers and innovative readouts. 

-    Apply a diversity of data analysing and visualization techniques to generate, analyze and document study results, as well as interpret and present data to multidisciplinary groups

-    Keep current on emergent technologies through literature review and scientific meetings

Minimum requirements

What You'll Bring to the Role:

•    MS, BS or equivalent degrees in molecular biology, biochemistry, cell biology, or related field with 2+ years of demonstrated ability, preferably in industry.
•    Expertise in in vitro methods including but not limited to molecular and cellular biology. Experience with iPSC-derived models are desirable.
•    Expertise in ex vivo/in vivo methods including biomarker and tissue analysis would be helpful
•    Knowledge and hands-on experience in developing and implementing assays (e.g. cell culture, qPCR, IHC/IF, ELISA, gene and protein analysis, imaging).
•    Data proficiency, including but not limited to data cleaning, wrangling, visualization, and conducting basic statistical analysis using Excel, R, Python or Prism. Eagerness to learn and leverage internal web-based tools for data exploration. Prior experience with omics data would be advantageous.
•    Ability to document, organize, communicate and present sophisticated data sets to multidisciplinary groups.
•    Ability to multi-task, work collaboratively as well as independently, be scientifically curious and self-motivated
•    Excellent oral and communication skills, analytical skills and interpersonal skills

Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

You’ll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity and Inclusion / EEO: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $66,000 to $126,000/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network